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Profound DNA methylomic differences between single- and multi-fraction alpha irradiations of lung fibroblasts

BACKGROUND: Alpha (α)-radiation is a ubiquitous environmental agent with epigenotoxic effects. Human exposure to α-radiation at potentially harmful levels can occur repetitively over the long term via inhalation of naturally occurring radon gas that accumulates in enclosed spaces, or as a result of...

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Detalles Bibliográficos
Autores principales: Vera-Chang, Marilyn N., Danforth, John M., Stuart, Marilyne, Goodarzi, Aaron A., Brand, Marjorie, Richardson, Richard B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10612361/
https://www.ncbi.nlm.nih.gov/pubmed/37891670
http://dx.doi.org/10.1186/s13148-023-01564-z