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DNA methylation of insulin signaling pathways is associated with HOMA2-IR in primary myoblasts from older adults
BACKGROUND: While ageing is associated with increased insulin resistance (IR), the molecular mechanisms underlying increased IR in the muscle, the primary organ for glucose clearance, have yet to be elucidated in older individuals. As epigenetic processes are suggested to contribute to the developme...
Autores principales: | , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10612387/ https://www.ncbi.nlm.nih.gov/pubmed/37898813 http://dx.doi.org/10.1186/s13395-023-00326-y |