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Intralesional Axitinib Injection Mitigates Hypertrophic Scar by Inhibiting Angiogenesis Pathway: A Preliminary Study in a Rabbit Ear Model

OBJECTIVE: High levels of VEGF and excessive angiogenesis contribute significantly to hypertrophic scar (HS) formation. Our study aimed to preliminarily investigate the effect of axitinib, a selective VEGF receptor tyrosine kinase inhibitor, on angiogenesis of HS and to explore its possible mechanis...

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Detalles Bibliográficos
Autores principales: Liu, Chuanbo, Tang, Liang, Hou, Chunsheng, Zhang, Jufang, Li, Jinsheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10612514/
https://www.ncbi.nlm.nih.gov/pubmed/37901151
http://dx.doi.org/10.2147/CCID.S430852