A biomimetic chip to assess subcutaneous bioavailability of monoclonal antibodies in humans

Subcutaneous (subQ) injection is a common route for delivering biotherapeutics, wherein pharmacokinetics is largely influenced by drug transport in a complex subQ tissue microenvironment. The selection of good drug candidates with beneficial pharmacokinetics for subQ injections is currently limited...

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Detalles Bibliográficos
Autores principales: Chandran Suja, Vineeth, Qi, Qin M, Halloran, Kevin, Zhang, Jifeng, Shaha, Suyog, Prakash, Supriya, Kumbhojkar, Ninad, Deslandes, Antoine, Huille, Sylvain, Gokarn, Yatin R, Mitragotri, Samir
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Research Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10612570/
https://www.ncbi.nlm.nih.gov/pubmed/37901442
http://dx.doi.org/10.1093/pnasnexus/pgad317

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10612570/
https://www.ncbi.nlm.nih.gov/pubmed/37901442
http://dx.doi.org/10.1093/pnasnexus/pgad317

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