Polygenic Propensity for Longevity, APOE-ε4 Status, Dementia Diagnosis, and Risk for Cause-Specific Mortality: A Large Population-Based Longitudinal Study of Older Adults

To deepen the understanding of genetic mechanisms influencing mortality risk, we investigated the impact of genetic predisposition to longevity and APOE-ε4, on all-cause mortality and specific causes of mortality. We further investigated the mediating effects of dementia on these relationships. Usin...

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Detalles Bibliográficos
Autores principales: Ajnakina, Olesya, Shamsutdinova, Diana, Stahl, Daniel, Steptoe, Andrew
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
THE JOURNAL OF GERONTOLOGY: Biological Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10613005/
https://www.ncbi.nlm.nih.gov/pubmed/37434484
http://dx.doi.org/10.1093/gerona/glad168

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10613005/
https://www.ncbi.nlm.nih.gov/pubmed/37434484
http://dx.doi.org/10.1093/gerona/glad168

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