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Palmitate and glucose increase amyloid precursor protein in extracellular vesicles: Missing link between metabolic syndrome and Alzheimer's disease

The metabolic syndrome (MetS) and Alzheimer's disease share several pathological features, including insulin resistance, abnormal protein processing, mitochondrial dysfunction and elevated inflammation and oxidative stress. The MetS constitutes elevated fasting glucose, obesity, dyslipidaemia a...

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Detalles Bibliográficos
Autores principales: Kim, Bhumsoo, Kang, Yoon‐Tae, Mendelson, Faye E., Hayes, John M., Savelieff, Masha G., Nagrath, Sunitha, Feldman, Eva L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10613125/
https://www.ncbi.nlm.nih.gov/pubmed/37898562
http://dx.doi.org/10.1002/jev2.12340