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Does statin suppress oxaliplatin-induced peripheral neuropathy in patients with colorectal cancer? A single-center observational study

BACKGROUND: Oxaliplatin-induced peripheral neuropathy (OIPN) is a common and dose-limiting toxicity that markedly limits the use of oxaliplatin and affects quality of life. Statins have been shown to exert neuroprotective effects in preclinical settings. The aim of the present study was to clarify w...

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Detalles Bibliográficos
Autores principales: Okamoto, Kazuaki, Nozawa, Hiroaki, Emoto, Shigenobu, Murono, Koji, Sasaki, Kazuhito, Ishihara, Soichiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10613143/
https://www.ncbi.nlm.nih.gov/pubmed/37897532
http://dx.doi.org/10.1007/s00520-023-08134-2