Loss of fragile WWOX gene leads to senescence escape and genome instability

Induction of DNA damage response (DDR) to ensure accurate duplication of genetic information is crucial for maintaining genome integrity during DNA replication. Cellular senescence is a DDR mechanism that prevents the proliferation of cells with damaged DNA to avoid mitotic anomalies and inheritance...

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Detalles Bibliográficos
Autores principales: Cheng, Hui-Ching, Huang, Po-Hsien, Lai, Feng-Jie, Jan, Ming-Shiou, Chen, Yi-Lin, Chen, Szu-Ying, Chen, Wan-Li, Hsu, Chao-Kai, Huang, Wenya, Hsu, Li-Jin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2023
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10613160/
https://www.ncbi.nlm.nih.gov/pubmed/37897534
http://dx.doi.org/10.1007/s00018-023-04950-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10613160/
https://www.ncbi.nlm.nih.gov/pubmed/37897534
http://dx.doi.org/10.1007/s00018-023-04950-1

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