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Recombinant immunotoxin induces tumor intrinsic STING signaling against head and neck squamous cell carcinoma

The innate immune stimulator of interferon genes (STING) pathway is known to activate type I interferons (IFN-I) and participate in generating antitumor immunity. We previously produced hDT806, a recombinant diphtheria immunotoxin, and demonstrated its efficacy against head and neck squamous cell ca...

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Detalles Bibliográficos
Autores principales: Xie, Guiqin, Shan, Liang, Yang, Cuicui, Liu, Yuanyi, Pang, Xiaowu, Teng, Shaolei, Wu, Tzyy-Choou, Gu, Xinbin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10613212/
https://www.ncbi.nlm.nih.gov/pubmed/37898690
http://dx.doi.org/10.1038/s41598-023-45797-7