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Recombinant immunotoxin induces tumor intrinsic STING signaling against head and neck squamous cell carcinoma
The innate immune stimulator of interferon genes (STING) pathway is known to activate type I interferons (IFN-I) and participate in generating antitumor immunity. We previously produced hDT806, a recombinant diphtheria immunotoxin, and demonstrated its efficacy against head and neck squamous cell ca...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10613212/ https://www.ncbi.nlm.nih.gov/pubmed/37898690 http://dx.doi.org/10.1038/s41598-023-45797-7 |