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Targeting cancer-associated adipocyte-derived CXCL8 inhibits triple-negative breast cancer progression and enhances the efficacy of anti-PD-1 immunotherapy

Cancer-associated adipocytes (CAAs), one of the primary stromal components, exhibit intimate crosstalk and release multiple cell factors mediating local and systemic biological effects. However, the role of CAAs in the regulation of systemic immune responses and their potential value in the clinical...

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Detalles Bibliográficos
Autores principales: Huang, Renhong, Wang, Zheng, Hong, Jin, Wu, Jiayi, Huang, Ou, He, Jianrong, Chen, Weiguo, Li, Yafen, Chen, Xiaosong, Shen, Kunwei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10613226/
https://www.ncbi.nlm.nih.gov/pubmed/37898619
http://dx.doi.org/10.1038/s41419-023-06230-z