XMAP: Cross-population fine-mapping by leveraging genetic diversity and accounting for confounding bias

Fine-mapping prioritizes risk variants identified by genome-wide association studies (GWASs), serving as a critical step to uncover biological mechanisms underlying complex traits. However, several major challenges still remain for existing fine-mapping methods. First, the strong linkage disequilibr...

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Detalles Bibliográficos
Autores principales: Cai, Mingxuan, Wang, Zhiwei, Xiao, Jiashun, Hu, Xianghong, Chen, Gang, Yang, Can
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10613261/
https://www.ncbi.nlm.nih.gov/pubmed/37898663
http://dx.doi.org/10.1038/s41467-023-42614-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10613261/
https://www.ncbi.nlm.nih.gov/pubmed/37898663
http://dx.doi.org/10.1038/s41467-023-42614-7

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