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XMAP: Cross-population fine-mapping by leveraging genetic diversity and accounting for confounding bias
Fine-mapping prioritizes risk variants identified by genome-wide association studies (GWASs), serving as a critical step to uncover biological mechanisms underlying complex traits. However, several major challenges still remain for existing fine-mapping methods. First, the strong linkage disequilibr...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10613261/ https://www.ncbi.nlm.nih.gov/pubmed/37898663 http://dx.doi.org/10.1038/s41467-023-42614-7 |