A tuft cell - ILC2 signaling circuit provides therapeutic targets to inhibit gastric metaplasia and tumor development

Although gastric cancer is a leading cause of cancer-related deaths, systemic treatment strategies remain scarce. Here, we report the pro-tumorigenic properties of the crosstalk between intestinal tuft cells and type 2 innate lymphoid cells (ILC2) that is evolutionarily optimized for epithelial remo...

Descripción completa

Detalles Bibliográficos
Autores principales: O’Keefe, Ryan N., Carli, Annalisa L. E., Baloyan, David, Chisanga, David, Shi, Wei, Afshar-Sterle, Shoukat, Eissmann, Moritz F., Poh, Ashleigh R., Pal, Bhupinder, Seillet, Cyril, Locksley, Richard M., Ernst, Matthias, Buchert, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10613282/
https://www.ncbi.nlm.nih.gov/pubmed/37898600
http://dx.doi.org/10.1038/s41467-023-42215-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10613282/
https://www.ncbi.nlm.nih.gov/pubmed/37898600
http://dx.doi.org/10.1038/s41467-023-42215-4

Ejemplares similares