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A circular RNA activated by TGFβ promotes tumor metastasis through enhancing IGF2BP3-mediated PDPN mRNA stability

Metastasis is the leading cause of cancer-related death, where TGFβ-induced epithelial-mesenchymal transition (EMT) process confers on cancer cells increased metastatic potential. However, the involvement of circRNAs in this process is still obscure. Here, we identify a TGFβ-induced circRNA called c...

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Detalles Bibliográficos
Autores principales: Li, Ke, Guo, Jiawei, Ming, Yue, Chen, Shuang, Zhang, Tingting, Ma, Hulin, Fu, Xin, Wang, Jin, Liu, Wenrong, Peng, Yong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10613289/
https://www.ncbi.nlm.nih.gov/pubmed/37898647
http://dx.doi.org/10.1038/s41467-023-42571-1