The identification of BCL-XL and MCL-1 as key anti-apoptotic proteins in medulloblastoma that mediate distinct roles in chemotherapy resistance

Medulloblastoma is the most common malignant paediatric brain tumour, representing 20% of all paediatric intercranial tumours. Current aggressive treatment protocols and the use of radiation therapy in particular are associated with high levels of toxicity and significant adverse effects, and long-t...

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Detalles Bibliográficos
Autores principales: Fitzgerald, Marie-Claire, O’Halloran, Philip J., Kerrane, Sean A., Ní Chonghaile, Triona, Connolly, Niamh M. C., Murphy, Brona M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10613306/
https://www.ncbi.nlm.nih.gov/pubmed/37898609
http://dx.doi.org/10.1038/s41419-023-06231-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10613306/
https://www.ncbi.nlm.nih.gov/pubmed/37898609
http://dx.doi.org/10.1038/s41419-023-06231-y

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