Lipidome and metabolome analyses reveal metabolic alterations associated with MCF-7 apoptosis upon 4-hydroxytamoxifen treatment

4-hydroxytamoxifen (OHT) is an anti-cancer drug that induces apoptosis in breast cancer cells. Although changes in lipid levels and mitochondrial respiration have been observed in OHT-treated cells, the overall mechanisms underlying these metabolic alterations are poorly understood. In this study, t...

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Detalles Bibliográficos
Autores principales: Nishimoto, Kazuki, Okahashi, Nobuyuki, Maruyama, Masaharu, Izumi, Yoshihiro, Nakatani, Kohta, Ito, Yuki, Iida, Junko, Bamba, Takeshi, Matsuda, Fumio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10613619/
https://www.ncbi.nlm.nih.gov/pubmed/37899460
http://dx.doi.org/10.1038/s41598-023-45764-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10613619/
https://www.ncbi.nlm.nih.gov/pubmed/37899460
http://dx.doi.org/10.1038/s41598-023-45764-2

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