TP53 Gene 72 Arg/Pro (rs1042522) single nucleotide polymorphism increases the risk and the severity of chronic lymphocytic leukemia

BACKGROUND: Genetic variations in TP53 gene are known to be important in chronic lymphocytic leukemia (CLL) and may cause its inactivation which is associated with an aggressive form of the disease. Single nucleotide polymorphism (rs1042522:G>C) in TP53 gene at codon 72 encodes for arginine (Arg)...

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Detalles Bibliográficos
Autores principales: Ounalli, Asma, Moumni, Imen, Mechaal, Amal, Chakroun, Aya, Barmat, Mbarka, Rhim, Rim El Elj, Menif, Samia, Safra, Ines
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Oncology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10613635/
https://www.ncbi.nlm.nih.gov/pubmed/37909012
http://dx.doi.org/10.3389/fonc.2023.1272876

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10613635/
https://www.ncbi.nlm.nih.gov/pubmed/37909012
http://dx.doi.org/10.3389/fonc.2023.1272876

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