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Promoting intestinal antimicrobial defense and microbiome symbiosis contributes to IL-22-mediated protection against alcoholic hepatitis in mice

BACKGROUND: The hepatoprotective effect of interleukin 22 (IL-22) has been reported in several models of liver injuries, including alcohol-associated liver disease (ALD). However, the intestinal role of IL-22 in alcoholic hepatitis remains to be elucidated. METHODS: Intestinal IL-22 levels were meas...

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Detalles Bibliográficos
Autores principales: Yue, Ruichao, Wei, Xiaoyuan, Hao, Liuyi, Dong, Haibo, Guo, Wei, Sun, Xinguo, Zhao, Jiangchao, Zhou, Zhanxiang, Zhong, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10613651/
https://www.ncbi.nlm.nih.gov/pubmed/37908362
http://dx.doi.org/10.3389/fimmu.2023.1289356