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Schistosomiasis-associated pulmonary hypertension unveils disrupted murine gut–lung microbiome and reduced endoprotective Caveolin-1/BMPR2 expression

Schistosomiasis-associated Pulmonary Arterial Hypertension (Sch-PAH) is a life-threatening complication of chronic S. mansoni infection that can lead to heart failure and death. During PAH, the expansion of apoptosis-resistant endothelial cells (ECs) has been extensively reported; however, therapeut...

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Detalles Bibliográficos
Autores principales: Marinho, Ygor, Villarreal, Elizabeth S., Aboagye, Sammy Y., Williams, David L., Sun, Jun, Silva, Claudia L. M., Lutz, Sarah E., Oliveira, Suellen D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10613683/
https://www.ncbi.nlm.nih.gov/pubmed/37908354
http://dx.doi.org/10.3389/fimmu.2023.1254762