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Proper development of long-lived memory CD4 T cells requires HLA-DO function

INTRODUCTION: HLA-DO (DO) is an accessory protein that binds DM for trafficking to MIIC and has peptide editing functions. DO is mainly expressed in thymic medulla and B cells. Using biochemical experiments, our lab has discovered that DO has differential effects on editing peptides of different seq...

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Detalles Bibliográficos
Autores principales: Song, Nianbin, Welsh, Robin A., Sadegh-Nasseri, Scheherazade
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10613709/
https://www.ncbi.nlm.nih.gov/pubmed/37908352
http://dx.doi.org/10.3389/fimmu.2023.1277609