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Proper development of long-lived memory CD4 T cells requires HLA-DO function
INTRODUCTION: HLA-DO (DO) is an accessory protein that binds DM for trafficking to MIIC and has peptide editing functions. DO is mainly expressed in thymic medulla and B cells. Using biochemical experiments, our lab has discovered that DO has differential effects on editing peptides of different seq...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Frontiers Media S.A.
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10613709/ https://www.ncbi.nlm.nih.gov/pubmed/37908352 http://dx.doi.org/10.3389/fimmu.2023.1277609 |