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The antidepressant effect of short- and long-term zinc exposition is partly mediated by P2X7 receptors in male mice

Background: As a member of the purinergic receptor family, divalent cation-regulated ionotropic P2X7 (P2rx7) plays a role in the pathophysiology of psychiatric disorders. This study aimed to investigate whether the effects of acute zinc administration and long-term zinc deprivation on depression-lik...

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Detalles Bibliográficos
Autores principales: Iring-Varga, Bernadett, Baranyi, Mária, Gölöncsér, Flóra, Tod, Pál, Sperlágh, Beáta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10613712/
https://www.ncbi.nlm.nih.gov/pubmed/37908978
http://dx.doi.org/10.3389/fphar.2023.1241406