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Genetic overlap for ten cardiovascular diseases: A comprehensive gene-centric pleiotropic association analysis and Mendelian randomization study

Recent studies suggest that pleiotropic effects may explain the genetic architecture of cardiovascular diseases (CVDs). We conducted a comprehensive gene-centric pleiotropic association analysis for ten CVDs using genome-wide association study (GWAS) summary statistics to identify pleiotropic genes...

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Detalles Bibliográficos
Autores principales: Liu, Zeye, Xu, Jing, Tan, Jiangshan, Li, Xiaofei, Zhang, Fengwen, Ouyang, Wenbin, Wang, Shouzheng, Huang, Yuan, Li, Shoujun, Pan, Xiangbin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10613921/
https://www.ncbi.nlm.nih.gov/pubmed/37908310
http://dx.doi.org/10.1016/j.isci.2023.108150