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Nitric oxide/paclitaxel micelles enhance anti-liver cancer effects and paclitaxel sensitivity by inducing ferroptosis, endoplasmic reticulum stress and pyroptosis

The objective of this study was to investigate the anticancer activities of biodegradable polymeric micelles composed of monomethoxy poly(ethylene glycol), polylactic acid, and nitric oxide (mPEG-PLA-NO) loaded with paclitaxel (PTX) as a nanomedicine delivery system. We aimed to compare the anticanc...

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Detalles Bibliográficos
Autores principales: Li, Huilan, Deng, Xiaoyu, Zhang, Ziwei, Yang, Zunhua, Huang, Hesong, Ye, Xide, Zhong, Linyun, Xu, Guoliang, Liu, Ronghua, Fang, Yuanying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10613954/
https://www.ncbi.nlm.nih.gov/pubmed/37908648
http://dx.doi.org/10.1039/d3ra04861f