The anti-cancer efficacy of a novel phenothiazine derivative is independent of dopamine and serotonin receptor inhibition

INTRODUCTION: An attractive, yet unrealized, goal in cancer therapy is repurposing psychiatric drugs that can readily penetrate the blood-brain barrier for the treatment of primary brain tumors and brain metastases. Phenothiazines (PTZs) have demonstrated anti-cancer properties through a variety of...

Descripción completa

Detalles Bibliográficos
Autores principales: Vanneste, Marion, Venzke, Anita, Guin, Soumitra, Fuller, Andrew J., Jezewski, Andrew J., Beattie, Sarah R., Krysan, Damian J., Meyers, Marvin J., Henry, Michael D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Oncology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10613967/
https://www.ncbi.nlm.nih.gov/pubmed/37909019
http://dx.doi.org/10.3389/fonc.2023.1295185

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10613967/
https://www.ncbi.nlm.nih.gov/pubmed/37909019
http://dx.doi.org/10.3389/fonc.2023.1295185

Ejemplares similares