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The anti-cancer efficacy of a novel phenothiazine derivative is independent of dopamine and serotonin receptor inhibition

INTRODUCTION: An attractive, yet unrealized, goal in cancer therapy is repurposing psychiatric drugs that can readily penetrate the blood-brain barrier for the treatment of primary brain tumors and brain metastases. Phenothiazines (PTZs) have demonstrated anti-cancer properties through a variety of...

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Detalles Bibliográficos
Autores principales:	Vanneste, Marion, Venzke, Anita, Guin, Soumitra, Fuller, Andrew J., Jezewski, Andrew J., Beattie, Sarah R., Krysan, Damian J., Meyers, Marvin J., Henry, Michael D.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2023
Materias:	Oncology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10613967/ https://www.ncbi.nlm.nih.gov/pubmed/37909019 http://dx.doi.org/10.3389/fonc.2023.1295185

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