Repurposing HLA genotype data of renal transplant patients to prevent severe drug hypersensitivity reactions

Introduction: Specific alleles in human leukocyte antigens (HLAs) are associated with an increased risk of developing drug hypersensitivity reactions induced by abacavir, allopurinol, carbamazepine, oxcarbazepine, phenytoin, lamotrigine, or flucloxacillin. Transplant patients are genotyped for HLA a...

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Detalles Bibliográficos
Autores principales: Manson, Lisanne E. N., Delwig, Sander J., Drabbels, Jos J. M., Touw, Daan J., De Vries, Aiko P. J., Roelen, Dave L., Guchelaar, Henk-Jan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Genetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10613976/
https://www.ncbi.nlm.nih.gov/pubmed/37908589
http://dx.doi.org/10.3389/fgene.2023.1289015

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10613976/
https://www.ncbi.nlm.nih.gov/pubmed/37908589
http://dx.doi.org/10.3389/fgene.2023.1289015

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