SFXN3 is Associated with Poor Clinical Outcomes and Sensitivity to the Hypomethylating Therapy in Non-M3 Acute Myeloid Leukemia Patients

BACKGROUND: DNA hypermethylation plays a critical role in the occurrence and progression of acute myeloid leukemia (AML). The mitochondrial serine transporter, SFXN3, is vital for one-carbon metabolism and DNA methylation. However, the impact of SFXN3 on the occurrence and progression of AML has not...

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Detalles Bibliográficos
Autores principales: Dong, Yuxuan, Jin, Fengbo, Wang, Jing, Li, Qingsheng, Huang, Zhenqi, Xia, Leiming, Yang, Mingzhen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Bentham Science Publishers 2023
Materias:
Life Sciences, Genetics & Genomics, Molecular Medicine, Genetics & Heredity
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10614111/
https://www.ncbi.nlm.nih.gov/pubmed/37491851
http://dx.doi.org/10.2174/1566523223666230724121515

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10614111/
https://www.ncbi.nlm.nih.gov/pubmed/37491851
http://dx.doi.org/10.2174/1566523223666230724121515

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