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SFXN3 is Associated with Poor Clinical Outcomes and Sensitivity to the Hypomethylating Therapy in Non-M3 Acute Myeloid Leukemia Patients
BACKGROUND: DNA hypermethylation plays a critical role in the occurrence and progression of acute myeloid leukemia (AML). The mitochondrial serine transporter, SFXN3, is vital for one-carbon metabolism and DNA methylation. However, the impact of SFXN3 on the occurrence and progression of AML has not...
Autores principales: | Dong, Yuxuan, Jin, Fengbo, Wang, Jing, Li, Qingsheng, Huang, Zhenqi, Xia, Leiming, Yang, Mingzhen |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Bentham Science Publishers
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10614111/ https://www.ncbi.nlm.nih.gov/pubmed/37491851 http://dx.doi.org/10.2174/1566523223666230724121515 |
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