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Characterization of SHARPIN knockout Syrian hamsters developed using CRISPR/Cas9 system
BACKGROUND: SHARPIN (SHANK‐associated RH domain interactor) is a component of the linear ubiquitination complex that regulates the NF‐κB signaling pathway. To better understand the function of SHARPIN, we sought to establish a novel genetically engineered Syrian hamster with SHARPIN disruption using...
Autores principales: | , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10614123/ https://www.ncbi.nlm.nih.gov/pubmed/36097701 http://dx.doi.org/10.1002/ame2.12265 |