Characterization of SHARPIN knockout Syrian hamsters developed using CRISPR/Cas9 system

BACKGROUND: SHARPIN (SHANK‐associated RH domain interactor) is a component of the linear ubiquitination complex that regulates the NF‐κB signaling pathway. To better understand the function of SHARPIN, we sought to establish a novel genetically engineered Syrian hamster with SHARPIN disruption using...

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Detalles Bibliográficos
Autores principales: Miao, Jinxin, Lan, Tianfeng, Guo, Haoran, Wang, Jianyao, Zhang, Guangtao, Wang, Zheng, Yang, Panpan, Li, Haoze, Zhang, Chunyang, Wang, Yaohe, Li, Xiu‐Min, Miao, Mingsan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Regular Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10614123/
https://www.ncbi.nlm.nih.gov/pubmed/36097701
http://dx.doi.org/10.1002/ame2.12265

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