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Hypoxia-Directed and Self-Immolative Theranostic Agent: Imaging and Treatment of Cancer and Bacterial Infections

[Image: see text] The impact of bacteria on cancer progression and treatment is becoming increasingly recognized. Cancer-associated bacteria are linked to metastases, reduced efficacy, and survival challenges. In this study, we present a sensitive hypoxia-activated prodrug, NR-NO(2), which comprises...

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Detalles Bibliográficos
Autores principales: Karan, Sanu, Cho, Mi Young, Lee, Hyunseung, Kim, Hyun Min, Park, Hye Sun, Han, Eun Hee, Sessler, Jonathan L., Hong, Kwan Soo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10614179/
https://www.ncbi.nlm.nih.gov/pubmed/37823731
http://dx.doi.org/10.1021/acs.jmedchem.3c01274