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Fighting Multidrug Resistance with Ruthenium–Cyclopentadienyl Compounds: Unveiling the Mechanism of P-gp Inhibition
[Image: see text] The search for more effective and selective drugs to overcome cancer multidrug resistance is urgent. As such, a new series of ruthenium-cyclopentadienyl (“RuCp”) compounds with the general formula [Ru(η(5)-C(5)H(4)R)(4,4′-R′-2,2′-bipy)(PPh(3))] were prepared and fully characterized...
| Autores principales: | , , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Chemical Society
2023
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10614197/ https://www.ncbi.nlm.nih.gov/pubmed/37616241 http://dx.doi.org/10.1021/acs.jmedchem.3c01120 |