Synthesis, Structure–Activity Relationships, Radiofluorination, and Biological Evaluation of [(18)F]RM365, a Novel Radioligand for Imaging the Human Cannabinoid Receptor Type 2 (CB2R) in the Brain with PET

[Image: see text] The development of cannabinoid receptor type 2 (CB2R) PET radioligands has been intensively explored due to the pronounced CB2R upregulation under various pathological conditions. Herein, we report on the synthesis of a series of CB2R affine fluorinated indole-2-carboxamide ligands...

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Detalles Bibliográficos
Autores principales: Teodoro, Rodrigo, Gündel, Daniel, Deuther-Conrad, Winnie, Kazimir, Aleksandr, Toussaint, Magali, Wenzel, Barbara, Bormans, Guy, Hey-Hawkins, Evamarie, Kopka, Klaus, Brust, Peter, Moldovan, Rareş-Petru
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10614203/
https://www.ncbi.nlm.nih.gov/pubmed/37816245
http://dx.doi.org/10.1021/acs.jmedchem.3c01035

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10614203/
https://www.ncbi.nlm.nih.gov/pubmed/37816245
http://dx.doi.org/10.1021/acs.jmedchem.3c01035

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