Violation of the Constant Genetic Effect Assumption Can Result in Biased Estimates for Non-Linear Mendelian Randomization

INTRODUCTION: Non-linear Mendelian randomization is an extension of conventional Mendelian randomization that performs separate instrumental variable analyses in strata of the study population with different average levels of the exposure. The approach estimates a localized average causal effect fun...

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Detalles Bibliográficos
Autor principal: Burgess, Stephen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: S. Karger AG 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10614256/
https://www.ncbi.nlm.nih.gov/pubmed/37651993
http://dx.doi.org/10.1159/000531659

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10614256/
https://www.ncbi.nlm.nih.gov/pubmed/37651993
http://dx.doi.org/10.1159/000531659

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