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Neutral sphingomyelinase inhibition promotes local and network degeneration in vitro and in vivo

BACKGROUND: Cell-to-cell communication is vital for tissues to respond, adapt, and thrive in the prevailing milieu. Several mechanisms mediate intercellular signaling, including tunneling nanotubes, gap junctions, and extracellular vesicles (EV). Depending on local and systemic conditions, EVs may c...

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Detalles Bibliográficos
Autores principales: Risner, Michael L., Ribeiro, Marcio, McGrady, Nolan R., Kagitapalli, Bhanu S., Chamling, Xitiz, Zack, Donald J., Calkins, David J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10614343/
https://www.ncbi.nlm.nih.gov/pubmed/37904133
http://dx.doi.org/10.1186/s12964-023-01291-1