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High-dose pharmaceutical-grade biotin in patients with demyelinating neuropathies: a phase 2b open label, uncontrolled, pilot study

BACKGROUND: We proposed to investigate high-dose pharmaceutical-grade biotin in a population of demyelinating neuropathies of different aetiologies, as a proof-of-concept. METHODS: Phase IIb open label, uncontrolled, single center, pilot study in 15 patients (three groups of five patients) with chro...

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Detalles Bibliográficos
Autores principales: Créange, Alain, Hutin, Emilie, Sedel, Frédéric, Le Vigouroux, Ludivine, Lefaucheur, Jean-Pascal
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10614347/
https://www.ncbi.nlm.nih.gov/pubmed/37899433
http://dx.doi.org/10.1186/s12883-023-03440-y