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Regulation of the integrin αVβ3- actin filaments axis in early osteogenic differentiation of human mesenchymal stem cells under cyclic tensile stress

BACKGROUND: Integrins are closely related to mechanical conduction and play a crucial role in the osteogenesis of human mesenchymal stem cells. Here we wondered whether tensile stress could influence cell differentiation through integrin αVβ3. METHODS: We inhibited the function of integrin αVβ3 of h...

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Detalles Bibliográficos
Autores principales: Peng, Yan, Qu, Rongmei, Yang, Yuchao, Fan, Tingyu, Sun, Bing, Khan, Asmat Ullah, Wu, Shutong, Liu, Wenqing, Zhu, Jinhui, Chen, Junxin, Li, Xiaoqing, Dai, Jingxing, Ouyang, Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10614380/
https://www.ncbi.nlm.nih.gov/pubmed/37904190
http://dx.doi.org/10.1186/s12964-022-01027-7