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Endometrial cancer (EC) derived G3BP1 overexpression and mutant promote EC tumorigenesis and metastasis via SPOP/ERα axis

BACKGROUND: Ras-GTPase-activating protein binding protein 1 (G3BP1) is an oncogenic factor, which highly expressed in a variety of cancers. In recent years, G3BP1 has been reported to promote the development of prostate cancer by inhibiting the degradation of AR through inhibiting SPOP. However, whe...

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Detalles Bibliográficos
Autores principales: Ge, Yidong, Jin, Jiabei, Chen, Gun, Li, Jinyun, Ye, Meng, Jin, Xiaofeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10614411/
https://www.ncbi.nlm.nih.gov/pubmed/37904149
http://dx.doi.org/10.1186/s12964-023-01342-7