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Protease-Activated Receptor 2 Controls Vascular Smooth Muscle Cell Proliferation in Cyclic AMP-Dependent Protein Kinase/Mitogen-Activated Protein Kinase Kinase 1/2-Dependent Manner

INTRODUCTION: Cardiovascular disorders are characterized by vascular smooth muscle (VSM) transition from a contractile to proliferative state. Protease-activated receptor 2 (PAR2) involvement in this phenotypic conversion remains unclear. We hypothesized that PAR2 controls VSM cell proliferation in...

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Detalles Bibliográficos
Autores principales: Williams, Madison D., Bullock, Michael T., Johnson, Sean C., Holland, Nathan A., Vuncannon, Danielle M., Oswald, Joani Zary, Adderley, Shaquria P., Tulis, David A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: S. Karger AG 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10614497/
https://www.ncbi.nlm.nih.gov/pubmed/37778342
http://dx.doi.org/10.1159/000532032