Inhalation of acidic nanoparticles prevents doxorubicin cardiotoxicity through improvement of lysosomal function

Doxorubicin (Dox) is an effective anticancer molecule, but its clinical efficacy is limited by strong cardiotoxic side effects. Lysosomal dysfunction has recently been proposed as a new mechanism of Dox-induced cardiomyopathy. However, to date, there is a paucity of therapeutic approaches capable of...

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Detalles Bibliográficos
Autores principales: Santin, Yohan, Formoso, Karina, Haidar, Fraha, Fuentes, Maria Del Pilar Oreja, Bourgailh, Florence, Hifdi, Nesrine, Hnia, Karim, Doghri, Yosra, Resta, Jessica, Champigny, Camille, Lechevallier, Séverine, Détrait, Maximin, Cousin, Grégoire, Bisserier, Malik, Parini, Angelo, Lezoualc'h, Frank, Verelst, Marc, Mialet-Perez, Jeanne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2023
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10614672/
https://www.ncbi.nlm.nih.gov/pubmed/37908733
http://dx.doi.org/10.7150/thno.86310

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10614672/
https://www.ncbi.nlm.nih.gov/pubmed/37908733
http://dx.doi.org/10.7150/thno.86310

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