Nanobody-mediated SPECT/CT imaging reveals the spatiotemporal expression of programmed death-ligand 1 in response to a CD8(+) T cell and iNKT cell activating mRNA vaccine

Rationale: Although promising responses are obtained in patients treated with immune checkpoint inhibitors targeting programmed death ligand 1 (PD-L1) and its receptor programmed death-1 (PD-1), only a fraction of patients benefits from this immunotherapy. Cancer vaccination may be an effective appr...

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Detalles Bibliográficos
Autores principales: Ertveldt, Thomas, Meulewaeter, Sofie, De Vlaeminck, Yannick, Olarte, Oscar, Broos, Katrijn, Van Calenbergh, Serge, Bourgeois, Stephanie, Deprez, Joke, Heremans, Yves, Goyvaerts, Cleo, Staels, Willem, De Smedt, Stefaan, Dewitte, Heleen, Devoogdt, Nick, Keyaerts, Marleen, Verbeke, Rein, Barbé, Kurt, Lentacker, Ine, Breckpot, Karine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2023
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10614673/
https://www.ncbi.nlm.nih.gov/pubmed/37908728
http://dx.doi.org/10.7150/thno.85106

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10614673/
https://www.ncbi.nlm.nih.gov/pubmed/37908728
http://dx.doi.org/10.7150/thno.85106

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