Engineered oncolytic bacteria HCS1 exerts high immune stimulation and safety profiles for cancer therapy

Background and rationale: Attenuated Salmonella typhimurium VNP20009 has been used to treat tumor-bearing mice and entered phase I clinical trials. However, its mild anticancer effect in clinical trials may be related to insufficient bacterial colonization and notable adverse effects with increasing...

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Detalles Bibliográficos
Autores principales: Sun, Yujie, Guo, Yanxia, Liu, Xiaoqing, Liu, Jinling, Sun, Honglai, Li, Zhongying, Wen, Min, Jiang, Sheng-Nan, Tan, Wenzhi, Zheng, Jin Hai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2023
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10614684/
https://www.ncbi.nlm.nih.gov/pubmed/37908720
http://dx.doi.org/10.7150/thno.87340

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10614684/
https://www.ncbi.nlm.nih.gov/pubmed/37908720
http://dx.doi.org/10.7150/thno.87340

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