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Upregulated FOXM1 stimulates chondrocyte senescence in Acot12(-/-)Nudt7(-/-) double knockout mice

Rationale: One of the hallmarks of osteoarthritis (OA), the most common degenerative joint disease, is increased numbers of senescent chondrocytes. Targeting senescent chondrocytes or signaling mechanisms leading to senescence could be a promising new therapeutic approach for OA treatment. However,...

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Detalles Bibliográficos
Autores principales: Song, Jinsoo, Kim, Ee Hyun, Yang, Jun-Ho, Kim, Donghyeon, Robby, Akhmad Irhas, Kim, Se-ah, Park, Sung Young, Ryu, Ji Hyun, Jin, Eun-Jung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10614692/
https://www.ncbi.nlm.nih.gov/pubmed/37908734
http://dx.doi.org/10.7150/thno.89033