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Engineering CAR-T cells for radiohapten capture in imaging and radioimmunotherapy applications

Rationale: The in vivo dynamics of CAR-T cells remain incompletely understood. Novel methods are urgently needed to longitudinally monitor transferred cells non-invasively for biodistribution, functionality, proliferation, and persistence in vivo and for improving their cytotoxic potency in case of...

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Detalles Bibliográficos
Autores principales: Kurtz, Keifer, Eibler, Laura, Dacek, Megan M., Carter, Lukas M., Veach, Darren R., Lovibond, Samantha, Reynaud, Emma, Qureshy, Sarah, McDevitt, Michael R., Bourne, Christopher, Monette, Sebastien, Punzalan, Blesida, Khayat, Shireen, Verma, Svena, Kesner, Adam L., Cheung, Nai-Kong V., Schöder, Heiko, Gajecki, Leah, Cheal, Sarah M., Larson, Steven M., Scheinberg, David A., Krebs, Simone
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10614694/
https://www.ncbi.nlm.nih.gov/pubmed/37908719
http://dx.doi.org/10.7150/thno.87489