Increased deformations are dispensable for cell mechanoresponse in engineered bone analogs mimicking aging bone marrow

Aged individuals and astronauts experience bone loss despite rigorous physical activity. Bone mechanoresponse is in-part regulated by mesenchymal stem cells (MSCs) that respond to mechanical stimuli. Direct delivery of low intensity vibration (LIV) recovers MSC proliferation in senescence and simula...

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Detalles Bibliográficos
Autores principales: Regner, Alexander M, DeLeon, Maximilien, Gibbons, Kalin D., Howard, Sean, Nesbitt, Derek Q., Lujan, Trevor J., Fitzpatrick, Clare K., Farach-Carson, Mary C, Wu, Danielle, Uzer, Gunes
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10614733/
https://www.ncbi.nlm.nih.gov/pubmed/37905032
http://dx.doi.org/10.1101/2023.09.24.559187

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10614733/
https://www.ncbi.nlm.nih.gov/pubmed/37905032
http://dx.doi.org/10.1101/2023.09.24.559187

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