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Mechanical coupling coordinates microtubule growth

During mitosis, kinetochore-attached microtubules form bundles (k-fibers) in which many filaments grow and shorten in near-perfect unison to align and segregate each chromosome. However, individual microtubules grow at intrinsically variable rates, which must be tightly regulated for a k-fiber to be...

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Detalles Bibliográficos
Autores principales: Leeds, Bonnibelle K., Kostello, Katelyn F., Liu, Yuna Y., Nelson, Christian R., Biggins, Sue, Asbury, Charles L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10614740/
https://www.ncbi.nlm.nih.gov/pubmed/37905093
http://dx.doi.org/10.1101/2023.06.29.547092