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Molecular Time Capsules Enable Transcriptomic Recording in Living Cells

Live-cell transcriptomic recording can help reveal hidden cellular states that precede phenotypic transformation. Here we demonstrate the use of protein-based encapsulation for preserving samples of cytoplasmic RNAs inside living cells. These molecular time capsules (MTCs) can be induced to create t...

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Detalles Bibliográficos
Autores principales: Parker, Mirae, Rubien, Jack, McCormick, Dylan, Li, Gene-Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10614764/
https://www.ncbi.nlm.nih.gov/pubmed/37905077
http://dx.doi.org/10.1101/2023.10.12.562053