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Quantifiable TCR repertoire changes in pre-diagnostic blood specimens among high-grade ovarian cancer patients

High grade serous ovarian cancer (HGOC) is a major cause of death in women. Early detection of HGOC usually leads to a cure, yet it remains a clinical challenge with over 90% HGOCs diagnosed at advanced stages. This is mainly because conventional biomarkers are not sensitive to detect the microscopi...

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Detalles Bibliográficos
Autores principales: Yu, Xuexin, Ye, Jianfeng, Hathaway, Cassandra A., Tworoger, Shelley, Lea, Jayanthi, Li, Bo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10614767/
https://www.ncbi.nlm.nih.gov/pubmed/37905034
http://dx.doi.org/10.1101/2023.10.12.562056